Case 3
Result
Unfortunately
this is not correct!
Abundant invasive tumor with cytoplasmic blush is seen, making discernment of true faint to weak membrane staining difficult and requiring examination at 40X. Staining along open spaces is present and should not be included in HER2 scoring if there is no other tumor cell membrane staining (see: red arrow).1
1. Ventana 4B5 Interpretation Guide (Roche) https://diagnostics.roche.com/us/en/landing-pages/breast-her2-low.html.
This tool has been developed by AstraZeneca and is for demonstration purposes, it is not meant to replace HER2 interpretation trainings.
The tool is intended for pathologists only.
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