Case 2

H&E staining

Fall 2 H&E Färbung

HER2 staining (4B5 Ventana/Roche)

Fall 2 HER2 Färbung 10x Fall 2 HER2 Färbung 20x Fall 2 HER2 Färbung 40x

How would you score
this IHC image?

IHC-0 IHC-1+ IHC-2+ IHC-3+

IHC= immunohistochemistry; H&E: hematoxylin/eosin staining; HER2= human epidermal growth factor receptor 2. Images provided by Roche from the Ventana 4B5 Interpretation Guide (https://diagnostics.roche.com/us/en/landing-pages/breast-her2-low.html)

This tool has been developed by AstraZeneca and is for demonstration purposes, it is not meant to replace HER2 interpretation trainings.
The tool is intended for pathologists only.

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